The Clinical Research Support Office (CRSO) selected Topsail to develop a custom web application for CRSO analysts to use to oversee and validate every ongoing clinical trial at Duke. The software has a highly specialized user-interface optimized to allow CRSO staff to evaluate the status of thousands of studies and tens of thousands of subjects more efficiently than was possible before the software was developed. As a result, the CRSO has realized an order of magnitude gain in the efficiency over their previous validation process.